Sintesis Dodekil β-Hidroksi Pelargonamida Melalui Reaksi Amidasi Dodekilamina dengan Asam β-Hidroksi Pelargonat yang Diturunkan dari Asam Risinoleat

Abstract

Ricinoleic acid that was be be obtained from hydrolysis castor oil can be oxidized by KMnO4 in base and acid condition to produced β-hydroxy pelargonic acid. The esterification of β-hydroxy pelargonic acid that still mixed with another fatty acid, with methanol in benzene as solvent using H2SO4 as catalyst gave methyl β-hydroxy pelargonate and can be separated from another fatty acid methyl esters by column chromatography. The amidation of methyl β-hydroxy pelargonate with dodecyl amine at 80°C for two hours produced dodecyl β-hydroxy pelargonamide, with 80% yield. This compound has a melting point of about 85-87°C, with HLB value 4.33. The identities of β-hydroxy pelargonic acid, methyl 13-hidroxy pelargonate and dodecyl β-hydroxy pelargonamide were confinned by FT-IR and 1H-NMR spectroscopy.