| dc.description.abstract | Background: Oil palm leaves contain alkaloids, flavonoids, saponins, tannins, and
steroids/triterpenoids, which are currently widely used as antibacterials. Acne curing cosmetics can be in the form of lotions with the advantages of being easily
applied and having high spreading and penetration power.
Purpose: This study aimed to formulate and test the antibacterial activity of lotion
preparations of ethanol extract of palm leaves as an anti-acne.
Methods: This research was carried out experimentally with the following stages:
collecting and processing samples, preparing extracts by maceration method,
phytochemical screening and characterization of simplicia and extracts, preparation
of test bacteria, testing of antibacterial activity of extracts, preparation of lotion
preparations of ethanol extract of palm oil leaves with concentrations 1%, 3% and
5%, antibacterial testing of lotion preparations and evaluation of the physical
quality of the ethanol extract lotion preparations of palm oil leaves.
Results: The evaluation showed that all lotion preparations were homogeneous
with an oil-in-water emulsion type (o/w), pH 6.5-7.0, viscosity ranged from 3201-
6371 mPas, spreadability 4.7-6.9 cm, stable for 12 weeks of storage at room
temperature (25℃) and cycling test. Irritation test showed negative results for the
irritation reaction parameter. The results of the antibacterial activity test for lotion
preparations with a diameter of inhibition against Propionibacterium acne and
Staphylococcus epidermidis, FI (blank) did not produce a diameter of inhibition
bacteria, FII (1%) 10.90 mm and 10.70 mm, FIII (3 %) 11.60 mm and 11.20 mm,
and FIV (5%) 12.60 mm and 12.50 mm.
Conclusion: Lotion preparations of ethanol extract from palm leaves with
concentrations of 1%, 3%, and 5% can be formulated and have an inhibitory effect
on bacteria | en_US |
