| dc.description.abstract | The purpose of this study was to qualitatively and quantitatively analyze the
hydroquinone content in night cream cosmetics circulating in Medan City and to
compare the HPLC method with UV-Vis Spectrophotometry in analyzing
hydroquinone in night cream preparations. This research was conducted because the
side effects caused by hydroquinone can cause contact dermatitis in the form of white
patches on the face or hyperpigmentation. Initial symptoms can include mild skin
irritation, heat, red, itching, or black spots on the face due to damage to melanocyte
cells. Analysis of the hydroquinone content of night cream at the beauty clinic in
Medan City using high-performance liquid chromatography and UV-Vis
spectrophotometer has been carried out. This study used a purposive sampling method
to take samples. The samples used were 6 preparations of night cream from beauty
clinics in Medan City and labeled A-F. Then the samples were analyzed. The results
showed that the samples coded A, B and E contained hydroquinone, while the samples
coded C, D and F did not contain hydroquinone. The highest hydroquinone was
obtained in sample B which was 4.78% and exceeded the allowable hydroquinone
threshold (2%). Research data shows that the concentration of hydroquinone in night
cream preparations. The use of both methods was used to see which method was more
appropriate in analyzing hydroquinone. From the results of the study, the UV-Vis
spectrophotometry method showed a clearer spectrum pattern compared to HPLC in
detecting the presence of hydroquinone in night cream preparations was 4,03% -
4,78%.. | en_US |
