| dc.description.abstract | Staphylococcus aureus is a bacterium that contributes to the development of oral
abscesses. If this oral abscess is not treated right away, odontogenic infection will develop.
Antimicrobial drugs can be used to prevent oral abscesses. Antimicrobial substances
made from natural materials are increasingly being used because they can make chemical
drugs less effective due to side effects and drug resistance. Pomegranates are among the
natural elements that may help prevent oral abscesses. Pomegranate peels contains active
compounds that can be utilized by the community as a medicine for healing abscesses. It
is widely known that pomegranate peel extract contains tannins, saponins, and flavonoids.
The study's purpose was to determine inhibitory ability of pomegranate peel extract on
the growth of Staphylococcus aureus. This kind of study is a laboratory experiment with
a post-test only control group design. The pomegranate peel extract was evaluated at
concentrations of 3,125%, 6,25%, 12,5%, 25%, and 50% with DMSO as a control
with four repititions. Kirby-Baurer Disc Diffusion is the technique used to test the
antibacterial efficacy. The Kruskal Wallis test findings revealed a p value of 0.001 on
inhibition, indicating that pomegranate peel extract had the ability to stop Staphylococcus
aureus bacteria from growing. The average value of the inhibition zone that resulted was
9.03 mm at 3.125% concentration, 9.63 mm at 6.25% concentration, 10.98 mm at 12.5%
concentration, 15.03 mm at 25% concentration, and 18.3 mm at 50% concentration.
According to the study's findings, pomegranate peel extract can inhibit the growth of
Staphylococcus aureus. | en_US |
