| dc.description.abstract | Periodontal tissue can develop gingival inflammation due to the number of
dental plaques and pathogenic microoganism. If left untreated, periodontal
pockets will form as the main clinical sign of periodontitis. The prevalence of
periodontitis in Indonesia is significant enough that effective periodontal disease
treatment is needed. Scaling-root planing is one type of initial phase periodontal
therapy. The problem that often arises is reduced accessibility and visibility at the
bottom of the deeper pocket (≥ 6 mm) so that local antimicrobial support therapy
is needed. Chlorhexidine periodontal chip are a local antimicrobial support
therapy that is commonly found but can cause side effects. Propolis is a honey byproduct
that has antibacterial, anti-inflammatory, and regenerating functions due
to its phenolic and flavonoid content. The purpose of this study is to conduct
phytochemical tests to determine the phenolic and flavonoid levels of 100%
Geniotrigona thoracica propolis extract as a candidate for 10% propolis chip,
which then studied for their biodegradation ability through biodegradation tests so
they can be used as supporting therapies. The design of this study is experimental
laboratory with 100% Geniotrigona thoracica propolis extract as the sample for
phytochemical tests and 15 10% propolis chips as the sample for biodegradation
tests. Phytochemical tests were carried out by measuring the absorbance of the
extract using a UV-Vis spectrophotometer and obtained total phenolic and
flavonoid levels of 5,303.3 mgGAE/Kg and 7,367.4 mg QE/Kg. The
biodegradation test was carried out by dripping 0.3 mL of 2.5% aqueous trypsin
solution onto 15 propolis chips for 8 days and the results were obtained that the
propolis chips experienced solubility in shape, size, consistency, and color as
parameters of biodegradation ability. In conclusion, 100% Geniotrigona thoracica
propolis extract contains phenolic and flavonoid levels as antibacterial, antiinflammatory,
and regenerating and propolis chips have biodegradation
capabilities | en_US |
