| dc.description.abstract | Introduction: Acute Coronary Syndrome (ACS) is used to describe the spectrum
of coronary artery disease. Precise and rapid diagnosis can reduce morbidity and
mortality. Troponin T is the determinant of the most sensitive marker in ACS but
it is not all hospitals have this marker because of expensiveness. Mean Platelet
Volume (MPV) is one of the components of a complete blood routine examination
and relatively cheap as marker in ACS.
Objective: To determine the sensitivity and specificity of MPV in detecting cases
of acute coronary syndrome.
Methods: Three hundred and twenty-five subjects research obtained from the
medical records of patients hospitalized Adam Malik Hospital were collected
during the period July 2013 to June 2014; 228 ACS patients met the inclusion
criteria. Complete blood laboratory data collection and troponin T. Statistical
analysis with diagnostic tests to see the accuracy of the MPV.
Results: Following 228 subjects showed a risk factor for age 2: 45 years of more
195 (85,5%). 122 subjects with hypertension (53,5%) and subjects who smoked
118 (51,8%) that suffered most ACS. Subjects with risk factors for diabetes
mellitus, obesity, menopause and dyslipidemia in this study is lower than non-
diabetic 161 (70,6%), obese 189 (82,9%), non menopause 196 (86%) and normal
Ii pig 210 (92, 1 % ). But there is not relation between risk factor with MPV and
troponin T statistically. The results of diagnostic tests MPV for the evaluation of
patients with ACS, sensitivity 92%, specificity 71 %, positive predictive value
95% and negative predictive value 58%.
Conclusion: Examination MPV levels can be used for diagnostic test in ACS
case. It has 92% and 71 % in sensitivity and specificity | en_US |
