| dc.description.abstract | Background: Sepsis is a pro-inflammatory state caused by systemic infection. As
sepsis progresses, multiple organ systems become affected with subsequent
increase in mortality. Elevated red cell distribution width (RDW) has been noted
with changes of other inflammatory markers and thus could potentially serve as a
means of assessing sepsis severity. In this study, we examine the correlation
between RDW with sepsis severity.
Objective: To determine differences between RDW value in infection without
sepsis and sepsis patients, sepsis and severe sepsis patients. Also to determine the
relationship between RDW with AP ACHE II score
Methods: Cross-sectional study was conducted on 41 patients with infection (27
men and 14 women) that had been admitted to H. Adam Malik hospital from
February 2016 to June 2016. Patients were categorized into three group namely
infection without sepsis, sepsis and severe sepsis based on clinical examination
and laboratory test results. Grouping criteria sepsis base on Pedoman Nasional
Pelayanan Kedokteran, Kemenkes 2014. Univariate and bivariate analysis
(independent t-test and Chi Square) were done using SPSS V.17
Results: There was a significant difference of mean RDW between the sepsis and
infection without sepsis groups (14,69 ± 2.31 and 13.39 ± 1.6, respectively) while
for sepsis and severe sepsis group there was no significant difference of mean
RDW. Likewise with AP ACHE II score, there was no significant difference
between the two groups.
Conclusion: RDW differed significantly between groups of sepsis and non sepsis
infection, but did not differ significantly between groups of sepsis with severe
sepsis | en_US |
