Hubungan Infeksi Helicobacter Pylori dengan Kejadian Gastroesophageal Reflux Disease (GERD) pada Etnik Batak di Desa Boho Kecamatan Sianjur Mulamula Kabupaten Samosir Provinsi Sumatera Utara

Abstract

Introduction: Gastroesophageal reflux disease (GERD) is one of the most common disorders of the digestive tract with an increasing prevalence. Epidemiological studies have found an increased prevalence of H. pylori infection with GERD. H. pylori has a high incidence in Asian countries. In Indonesia, the incidence of H. pylori infection remains unclear and controversial. Aim: This research aims to analyse relationship between H. pylori infection with risk of GERD in Batak ethnicity in BOHO Village, Sianjur Mulamula District, Samosir Regency, North Sumatra Province. Methods: This research is a cross-sectional analytical study. Research subjects were asked to fill out a demographic questionnaire, GERD-Q questionnaire, and perform a fecal antigen test (FAT). Results: A total of 100 participants who met the criteria were included in this study. The majority of research subjects were male, had normal BMI, and had no history of smoking or taking NSAIDs. Twenty percents of participants had a risk of GERD and positive FAT results were found in 17% of participants. Conclusion: Chi-square test showed no association between H. pylori infections and the risk of GERD with p-value of 0.741.