Faktor yang Berhubungan dengan Kualitas Hidup Pasien Tuberkulosis Paru di Poliklinik TB-DOTS Rumah Sakit Prof. Chairuddin P. Lubis USU Medan

Abstract

Background. Indonesia is the second country in the world with the highest burden of tuberculosis (TB). Pulmonary TB (PTB) is one of the global health issues that can substantially affect quality of life (QOL). Objectives. This study aimed to analyze factors associated with the QOL of PTB patients. Methods. This study was an analytical observational study with a cross-sectional design. The study sample was 100 PTB patients aged ≥18 years undergoing treatment at the TB-DOTS outpatient clinic of Prof. Chairuddin P. Lubis Hospital, Universitas Sumatera Utara, from August to October 2023. The sampling technique used was consecutive sampling through face-to-face interviews using the WHOQOL-BREF questionnaire. The analysis used was frequency distribution analysis, the chi-square test, and the logistic regression test. Results. The results of the bivariate analysis using the chi-square test showed that there was a significant relationship between age (p = 0.022), family income (p = 0.005), duration of treatment (p <0.001), and adverse drug reactions (ADRs) (p = 0.040) with overall QOL. The results of the multivariate analysis using the logistic regression test showed that there was a significant relationship between family income (p = 0,007, OR = 3,685, 95% CI = 1,432−9,479) and duration of treatment (p <0.001, OR = 5.643, 95% CI = 2.139–14.888) with the deterioration of overall QOL. Conclusion. The bivariate analysis showed a significant relationship between age, family income, duration of treatment, and ADRs with overall QOL. The multivariate analysis showed a significant relationship between family income and duration of treatment with the deterioration of overall QOL, and the duration of treatment was the factor that most influenced the deterioration of overall QOL.