Pengaruh Efektivitas Ekstrak Etanol Kayu Bajakah (Spatholobus sp.) terhadap Pertumbuhan Bakteri Staphylococcus aureus ATCC 25923

Abstract

Introduction. Infectious diseases are still an important issue for Indonesia. One of the opportunistic bacteria that causes various infectious diseases is Staphylococcus aureus. There is a need for new alternative treatments that have the same high potential as antibiotics. Bajakah wood (Spatholobus sp.) is a plant that grows abundantly in the tropical forests of Central Kalimantan. This plant has the potential to be antibacterial because it contains secondary metabolite compounds, namely alkaloids, tannins and glycosides. Objective. This research aims to determine the effectiveness of Bajakah wood (Spatholobus sp.) on the growth of S. aureus ATCC 25923 bacteria through testing ethanol extract. Method. In this research, three different methods were used, the disc method, the well method and the whatman paper method using a concentration of 5%; 15%; 25%; 50% and 100% extract. Results and Discussion. The results showed that the ethanol extract of Bajakah Wood (Spatholobus sp.) had antibacterial activity against S. aureus ATCC 25923 at the lowest concentration, namely 5%. The disk method obtained an average inhibition zone of 11.1 mm, the well method obtained an average inhibition zone of 16.8 mm and the whatman paper method obtained an average inhibition zone of 10.8 mm. Conclusion. From this research, the ethanol extract of Bajakah wood (Spatholobus sp.) has potential as an antibacterial against S. aureus bacteria with its secondary metabolite compounds.