Gambaran Profil Hemostasis pada Pasien Kanker Payudara dan Kanker Paru di RSUP H. Adam Malik Medan

Abstract

Introduction. Hemostasis is an endogenous mechanism that protects the body against bleeding and blood loss, including in cancer patients. This system includes plasma factors, platelets and the blood vessel wall in cancer patients., the hemostasis mechanism reflects the balance between procoagulant and anticoagulant mechanisms involved in the fibrinolytic process. ObjectiveObjective. To determine the hemostasis profile including PT, APTT, TT, D dimer, Fibrinogen. Methods. This study is a descriptive study using a cross sectional design. Data collection was done by non probability sampling technique with consecutive sampling method using medical records. The research subjects were breast cancer and lung cancer patients at H. Adam Malik Hospital Medan, totaling 179 people. ResultsResults. breast cancer APTT, TT, and fibrinogen were normal with the number of APTT (47.9%) TT (52.1%) and fibrinogen (65.8%). While PT, D dimer increased, where PT elongated as much as (80.2%) fibrinogen (56.2%). lung cancer PT, fibrinogen, d dimer relatively increased with the number of patients PT (70.9%) fibrinogen (51.2%) d dimer (80.2%). While the picture of APTT, TT values is normal with the number of APTT (46.5%) and TT (50.0%). Conclusion. In lung cancer PT, fibrinogen, d dimer are relatively increased, while the picture of APTT, TT values is normal. In breast cancer APTT, TT, and fibrinogen were normal, while PT, D dimer increased.