| dc.description.abstract | Background:
Children with epilepsy require appropriate management, because uncontrolled epilepsy
will increase the risk of morbidity and mortality. Antiepileptic drugs that are consumed in
the long term also cause side effects, one of which is hyponatremia that can cause
severe conditions for children with epilepsy. This study to determine the correlation
between anti epileptic drugs and the outcome of hyponatremia in childen with epilepsy
at the H. Adam Malik Hospital Medan
Metode
Analytical analyses with crossectional study in children with epilepsy aged 1 years up to
18 years at the H. Adam Malik Medan hospital from Juni – September 2022. The patient
had experienced other etiology of hyponatremia and gotten other treatment which had
side effect hyponatremia were exclude. Assessment of these variables with Chi Square
test and alternative Fisher’s Exact test. These analyses used prevalence ratio (RP) and
p value (p<0,05) with convidence interval (CI) 95%.
Results:
A total of 120 children with epilepsy were analyzed, and approximately 29 children had
hyponatremia. Chi square test analysis showed that were no significant correlation
between use of antiepileptic drugs and hyponatremia (p=0,861), duration treatment and
hyponatremia (p= 0,672), antiepileptic dose and hyponatremia (p>0,05). Fisher’s exact
test analysis showed that was no significan correlation between types of antiepileptic
drugs and hyponatremia (p>0,05).
Conclusion:
There was no significant correlation use of antiepileptic drugs, duration treatment, types
of antiepileptic drugs, antiepileptic dose and hyponatremia in children with epilepsy. | en_US |
