Faktor-Faktor yang Berhubungan dengan Hasil Pengobatan pada Pasien HIV/AIDS dengan Toksoplasmosis Serebri di Rumah Sakit Umum Pusat Haji Adam Malik Medan Tahun 2022-2023

Abstract

Introduction. Cerebral toxoplasmosis is a primary opportunistic infection in HIV/AIDS patients. Cerebral toxoplasmosis is closely associated with poor treatment outcomes in HIV patients due to an inadequate immune system. However, it does not rule out the possibility of treatment outcomes resulting in disability due to lesions in the brain parenchymal or patients recovering from T. gondii infection without disability. Objective. To identify factors related to treatment outcomes in HIV/AIDS patients with cerebral toxoplasmosis at RSUP Haji Adam Malik Medan from 2022 to 2023. Method. This study used a predictive multivariate analytical method with a cross-sectional design. The inclusion criteria for this research were HIV/AIDS patients with cerebral toxoplasmosis documented in the medical records of RSUP Haji Adam Malik Medan from 2022 to 2023. Result and Discussion. In bivariate analysis, ten variables were tested using chi-square test or fisher’s exact test, and only the leukocyte count showed a significant p-value (p = 0,029). Logistic regression test results indicated a p-value for the leukocyte count of 0,050 (OR 0,096; CI 0,009-1,004), lymphocyte count of 0,770 (OR 0,792; CI 0,116-3,777), and eosinophil count of 0,124 (OR 0,238; CI 0,038-1,484). Conclusion. No variable significantly influences patient treatment outcomes.