| dc.description.abstract | Background. Hyperthyroidism is a form of thyrotoxicosis characterized by
elevated levels of Thyroid Stimulating Hormone (TSH) and free Thyroxine (T4) in
the circulation due to abnormal secretion of thyroid gland. Increased thyroid
hormone levels lead to alteration in the basal metabolic rate (BMR) with increased
vital and metabolic functions as manifestations and clinical signs such as goitre,
tachycardia, tremors, weight loss, heat intolerance, sweating, irritability, and
menstrual disturbances. Common aetiologies of hyperthyroidism include Grave’s
disease, toxic adenoma, and multinodular goitre. Aim. To determine the prevalence
of hyperthyroidism based on the Wayne index among medical students at the
University of North Sumatera Faculty of Medicine. Method. This research is an
observational analytical study with a cross-sectional design. The research sample
was selected using consecutive sampling technique, consist of 90 individuals
selected from September to October 2023. The measurement instruments used
include examination sheets involving interviews and physical examinations. Data
were processed using ISM SPSS version 27. Result. The prevalence of
hyperthyroidism based on Wayne index in students of the Faculty of Medicine, USU
showed toxic hyperthyroidism at 2,2%, equivocal 16,7% and euthyroid 81,1%, with
a higher incidence in females compared to males (3:1). Among 17 hyperthyroid
respondents, there were 6 underweight,6 normal and 5 obese respondents as well as
6 respondents with a family history of the condition. The chi square test results for
risk factors and hyperthyroidism incidence showed p-values based on gender
0,0015, underweight 0,0015, normal weight 0,849, overweight 0,065, 0bese 0,557,
and family history 0,001. Conclusion. The prevalence of hyperthyroidism in
students of the Faculty of Medicine, USU is 2,2% and there is a strong correlation
between gender, underweight BMI, and family history with the occurrence of
hyperthyroidism. | en_US |
