Hubungan Kadar Trigliserida dengan Tingkat Keparahan Akne Vulgaris pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara

Abstract

Background : Triglycerides or what is often called triglycerol are a type of fat found in the blood and various types of organs. Triglycerides are formed from glycerol and fat in food. The increasing of triglycerides can escalate the production of androgen hormones and sebum levels in the skin which enhance the severity of acne vulgaris. Acne vulgaris is an inflammatory disorder of the pilosebaceous unit that runs chronically and can recover on its own. It is triggered by Cutibacterium acnes in adolescence under the influence of normal circulating Dehydroepiandosterone hormone. Objective : This study aims to determine the relationship between triglyceride levels in the blood and the severity of acne vulgaris in students at the Faculty of Medicine, Universitas Sumatera Utara. Methods: This research used a quantitative study using an unpaired cross sectional design. The sample was 95 students from the Faculty of Medicine, Universitas Sumatera Utara who has acne vulgaris. The sample was determined by using the non-probability sampling technique of the purposive sampling method. The data collection tool used an observation sheet by observing the results of triglyceride levels using lipid pro and carrying out the classification of Lehmann et al to determine the severity of acne vulgaris. Results and Discussion: There were 49 people (51.6%) with an optimal degree of triglyceride levels, 15 people (15.8%) with a desirable degree, 29 people (30.5%) with a high degree, 2 people (2.1%) with a very high degree, while there were 57 people (60%) with a mild degree of acne vulgaris, 27 people (28.4%) with a moderate degree, and 11 people (11.6%) with a severe degree. Conclusion: Triglyceride levels have a relationship with the severity of acne vulgaris.