Hubungan Laktat Albumin Ratio dengan Sofa Score sebagai Prediktor Pasien Sepsis di Ruang Intensive Care RSUP Haji Adam Malik Medan

Abstract

Background: Sepsis is a life-threatening organ dysfunction due to dysregulation of the host response to infection which causes systemic changes, namely an increase in the serum lactate/albumin ratio which is associated with mortality. Methods: This study is a clinical observational analytical study with a prospective cohort design at fittingAdult patients diagnosed with sepsis in the integrated inpatient ward and intensive care ward at Haji Adam Malik General Hospital, Medan. The subject sampling technique used was non-probability sampling with a consecutive sampling method where 50 subjects were required. Bivariate analysis used the Pearson correlation test and the linear relationship between the albuminlactate ratio value and SOFA score used linear regression. A 95% confidence interval with a p value <0.05 was considered significantly significant Results: The results of the research on the first day found that the average H1 LAR ratio was 0.59 + 0.51 (0.12-2.26) and the average H1 SOFA score was 7.32 + 1.88 (7) where the r value was obtained. of 0.726 which indicates a high and significant correlation between Lactate Albumin Ratio and SOFA Score as a predictor of sepsis patients (p value = 0.000, p<0.05). On the third day, the average H3 LAR ratio was 0.12 + 0.29 (0.21-0.47) and the average H3 SOFA score was 9.58 + 2.01 (10) where an r value of 0.33 was found. indicates a very low and insignificant correlation between Lactate Albumin Ratio and SOFA Score as a predictor of sepsis patients (p value = 0.818, p > 0.05). Conclusion: The lactate-albumin ratio is strongly correlated with the SOFA score on the first day of adult patients diagnosed with sepsis in integrated inpatient wards and intensive care wards.