Efektivitas Obat Kumur Ekstrak Biji Pinang (Areca catechu L.) dalam Menghambat Pertumbuhan Bakteri Staphylococcus aureus (In Vitro)

Abstract

Periodontal disease is chronic inflammation of the periodontal tissue which is initially induced by plaque-forming bacteria, one of which is Stapylococcus aureus. Plaque formation can be inhibited by controlling plaque mechanically, chemically, or a combination of both. Chemical plaque control using chlorhexidine will cause several side effects, so many researchers have finally begun to develop mouthwash made from herbal ingredients. Areca nuts (Areca catechu L.) contains flavonoids, tannins, alkaloids, terpenoids and quinones which have antibacterial activity. The aim of this research is to analyze and determine the effectiveness of areca nut extract mouthwash (Area catechu L.) against growth of S. aureus. This type of research is laboratory experimental research with post-test only control group design. This research sample is S. aureus ATCC®29213. This research was tested using the Kirby-Baurer (disc paper) diffusion method on the Nutrient Agar (NA) media with five repetitions then observations were made. The results of this study indicate that areca nut extract mouthwash (Areca catechu L.) concentrations of 2.5%, 5%, and 10% have inhibitory zone diameters of 6.88 mm, 8.24 mm, and 8.96 mm respectively which are included in the medium category. Chlorhexidine gluconate mouthwash 0.2% (positive control) has the largest diameter of the inhibition zone of 11.62 mm. Basic mouthwash is not effective because a clear zone is not formed. These differences are meaningful statistically.