Uji Aktivitas Antibakteri Ekstrak Buah Rimbang (Solanum torvum Sw.) terhadap Pertumbuhan Bakteri Streptococcus mitis secara In Vitro

Abstract

The oral cavity is a place where microorganisms are gathered and houses more than 700 species of microbial organisms, including bacteria, fungi, viruses and protozoa. Streptococcus mitis is a type of gram-positive bacterium that is commonly found in normal human flora, especially in the mouth and upper respiratory tract. Although generally non-pathogenic, Streptococcus mitis can be an opportunistic pathogen and contribute to infection in humans, the increasing problem of resistance is causing the need for new antimicrobial drugs that can cope with resistance problems is also increasing, therefore it is necessary to take alternative antibacterial drugs such as from medicinal plant ingredients to cope. Therefore, researchers see an opportunity to exploit the potential of nature as an alternative treatment ingredient. One of the ingredients used is Solanum torvum Sw., which is an herbal plant that has an antibacterial effect on Streptococcus mitis bacteria. This research method is experimental laboratory. The study used an extract of rimbang fruit with a number of concentrations of 12.5%, 25%, 50%, 100%, positive control, and negative control which was then applied to the surface of the disc paper to see the barrier zone of various concentrations. The test results were analyzed with one-way ANOVA and Post Hoc (LSD) tests. The results showed average concentration values of 12.5% (7,500mm), 25% (8.420mm), 50% (12.25mm) and 100% (16.17mm) positive control (21.270mm), and negative control. (0mm). The results of data analysis using the one-way Anova test showed a significant value of p=0,000 (p<0,05). It states that Ho rejected or Solanum torvum Sw. has an inhibitory power against Streptococcus mitis bacteria. Furthermore, the results of the post-hoc LSD test showed a degree of fertility p=0,000 at each concentration, except at a concentration of 12.5% and 25% which did not differ significantly in inhibiting Streptococcus mitis.