Efektivitas Gel Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.) 10% terhadap Penyembuhan Stomatitis Aftosa Rekuren

Abstract

Recurrent Aphthous Stomatitis (RAS) is a common oral mucosal disease. The treatment of RAS is challenging because the etiology remains unknown, and it is managed symptomatically. Andaliman fruit extract gel is one of the traditional remedies that can be used to treat RAS due to its anti-inflammatory, antibacterial, and antioxidant effects, reducing pain and expediting the healing process. The purpose of this study was to determine the effectiveness of 10% andaliman fruit extract gel on SAR healing. This research is a quasi-experimental research with pretest-posttest one group design. The sampling technique was done by purposive sampling. This study involved 16 active students of Faculty of Dentistry, University of North Sumatera who suffered from minor type SAR. Data collection was carried out by conducting an initial examination of SAR by looking at halo erythema, ulcer size, and pain scale then administered 10% andaliman extract gel and controlled every day for the next three days. Data analysis in this study used Friedman Test and Repeated Anova to determine differences in SAR observations before and after treatment. This study showed significant results on the reduction of halo erythema p=0.000 (p<0.05), ulcer size p=0.000 (p<0.05), and pain scale p=0.000 (p<0.05) in the examination, first control, second control and third control. The conclusion of this study is that the administration of 10% andaliman fruit extract gel showed a significant reduction in halo erythema, ulcer size, and pain scale in SAR.