Hubungan Nilai Total Lymphocyte Count terhadap Skor Sofa pada Pasien Sepsis yang Dirawat di ICU RSUP Haji Adam Malik Medan

Abstract

Background: Sepsis is a life-threatening organ dysfunction due to dysregulation of the host's response to infection which causes systemic changes, namely a decrease in the Total Lymphocyte Count value which is related to mortality. Method: This research is an observational analytical study with a cross sectional approach in adult patients diagnosed with sepsis in integrated inpatient wards and intensive care wards at Haji Adam Malik Hospital Medan. The subject sampling technique used was non-probability sampling with a consecutive sampling method where 115 subjects were required. Bivariate analysis used the Spearman correlation test on the Total Lymphocyte Count value and SOFA score with a 95% confidence interval with a p value <0.05 considered significantly significant. Results: The results of the research on the first day found that the average lymphocyte count was 0.92 + 0.29 (0.78) and the average SOFA score was 9.96 + 2.88 (11) where an r value of -0.783 was obtained which indicates a correlation. high and significant negative relationship between lymphocyte count and SOFA Score as a predictor of sepsis patients (p value = 0.001, p <0.05). Conclusion: lymphocyte count has a strong negative correlation with the SOFA score in adult patients diagnosed with sepsis in integrated inpatient wards and intensive care wards.