Penerapan Regresi Cox untuk Menganalisis Faktor yang Memengaruhi Laju Kesembuhan Pasien Demam Berdarah Dengue (DBD) di Rumah Sakit Advent Medan

Abstract

Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus which is transmitted by the Aedes Aegypty mosquito. DHF is often found in subtropical and tropical areas such as Indonesia. This study aims to analyze factors that influence the recovery rate of dengue fever patients at Advent Hospital Medan. This type of research is a retrospective cohort with a sample of 100 dengue fever patients. This study uses Cox regression to determine the factors that influence the recovery rate of dengue fever patients. Of the 100 data on dengue fever patients who were hospitalized at the Advent Hospital Medan, there were 59 male patients (59%) and 41 female patients (41%). The recovery time for dengue fever patients using the Life Table method shows a median survival of 4,88 days. The results of the Log-Rank test using the Kaplan-Meier method show that there is a relationship between the variables body temperature and hematocrit and the recovery rate of dengue fever patients at the Advent Hospital Medan. From the extended Cox regression analysis, it shows that the hazard ratio value of the body temperature variable is 1,087 (95% CI = 0,577–2,046), meaning that patients with a body temperature of 350 – 37,50C (normal) are likely to recover 1,087 times faster than patients with a body temperature of > 37,50C (fever). The hazard ratio value of the hematocrit variable is 0,826 (95% CI = 0,51 –1,328), meaning that patients with hematocrit levels < 36% are likely to recover 0,826 times longer than patients with hematocrit levels ≥ 36% . Medical personnel are expected to pay special attention to dengue fever patients by focusing on high body temperatures and low hematocrit levels which can affect the patient's recovery rate