dc.description.abstract | Background: Premature aging is damage that occurs to the skin due to free radicals.
Red ginger rhizome contains flavonoid compounds namely gingerol, shogaol and
resin which have antioxidant activity so as to prevent premature aging. Peel-off
masks have the ability to cleanse and remove dead skin cells on the face where
regular use can reduce fine wrinkles on the face. Gelatin has the power to gel well
and forms a thin elastic layer so that it can be used as a gelling agent in peel-off
masks.
Objective: To formulate and evaluate a peel-off mask containing ethanol extract of
red ginger rhizome with tilapia scales gelatin base and perform anti-aging testing
on facial skin.
Methods: The research method include the preparation of ethanol extract of red
ginger rhizome by maceration method using 70% ethanol solvent. Phytochemical
screening was conducted on simplisia and ethanol extract of red ginger rhizome.
Peel-off mask preparations were formulated with varying concentrations of 3%
gelatin (F0), 1% (F1), 2% (F2), 3% (F3) and without gelatin (F4) as well as the
addition of 5% red ginger rhizome ethanol extract to formulas F1, F2, F3 and F4.
The peel-off mask preparations were evaluated including organoleptic test,
homogeneity, pH, viscosity, spreadability, adhesiveness, drying time, stability test,
irritation test and anti-aging activity test on volunteer skin using a skin analyser
with parameters of moisture, pores, spots and wrinkles. Treatment was carried out
by using peel-off masks twice a week for four weeks. Data was then analysed using
statistical tests, namely Kruskal-Wallis test and Mann-Whitney test.
Results: The results of phytochemical screening of simplisia and ethanol extract of
red ginger rhizome showed the presence of alkaloid compounds, flavonoids,
glycosides, tannins, saponins and steroids. The peel-off mask preparation has a
distinctive smell of ginger, homogeneous, pH 5,01-5,63, viscosity 2115 cPs-2637
cPs, diameter of spreadability 5,66-6,18 cm, adhesion 5-12 seconds, drying time
20-26 minutes, stable for 12 weeks of storage at room temperature and does not
irritate the skin. Anti-aging activity testing showed that F0 (blank) with F1, F2, F3
and F4 had significant differences in restoring facial skin conditions (p<0,05).
Conclusion: Ethanol extract of red ginger rhizome can be formulated as a peel-off
mask preparation with tilapia scales gelatin base. The peel-off mask of ethanol
extract of red ginger with gelatin base has anti-aging activity on facial skin. The
higher the concentration of gelatin, the higher the viscosity and adhesiveness, the
lower the pH, spreadability and drying time. The best peel-off mask preparation is
at 2% gelatin concentration (F2). | en_US |