Analisis Efektivitas Biaya Terapi Obat Hipertensi pada Pasien Penyakit Stroke Iskemik di RSUP H. Adam Malik Medan

Abstract

Background: According to basic health research in 2018, the cost of stroke health services for stroke disease was the highest cost of 2.56 trillion rupiah in 2018. The number of stroke patients increases every year so the cost of health services automatically increases. One of the risk factors for stroke is hypertension, the use of appropriate antihypertensive drugs is necessary for stroke patients. It is necessary to select antihypertensives with low cost and guarantee the effectiveness of patient is therapy. Objective: To analyze the cost effectiveness of antihypertensive therapy models in ischemic stroke in patients hospitalized at H. Adam Malik Hospital Medan. Method: The type of research used cohort retrospective where the data come from the medical records of ischemic stroke inpatients at the H. Adam Malik Medan Hospital which was financed by the social health insurance administration body for the period January December 2023. The Cost Effective Ratio (CER) and Incremental Cost Effective Ratio (ICER) methods were used to analyze the use of the most cost effective. Results: This study 172 patients who met the inclusion criteria were selected as sample for this study. The majority of the participants were male (57%), with the largest proportion of individuals in the 60 69 age group (42%). The calculation of the CER value demonstrated that the lowest CER value was observed in the combination of Amlodipine 10 mg + Bisoprolol 2.5 mg (IDR.902), followed by Amlodipine 10 mg + Candesartan 16 mg (IDR.1.277), Amlodipine 5 mg (IDR.1.529), Amlodipine 10 mg (IDR.1.855), Bisoprolol 2.5 mg + Candesartan 16 mg (IDR.2.173), dan based on the calculation of the ICER value, the lowest ICER value is obtained by Amlodipine 10 mg + Bisoprolol 2.5 mg ( 92.312) which is in the second. Conclusion: This study showed that the most Cost effective of antihypertensive in ischemic stroke inpatient is Amlodipine 10 mg + Bisoprolol 2.5 mg.