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dc.contributor.advisorSumaiyah
dc.contributor.authorGulo, Jevon Three Kartika
dc.date.accessioned2024-09-05T04:05:49Z
dc.date.available2024-09-05T04:05:49Z
dc.date.issued2024
dc.identifier.urihttps://repositori.usu.ac.id/handle/123456789/96738
dc.description.abstractBackground: Hand skin is the part of the body's skin that is most often exposed to sunlight so it easily loses moisture and becomes rougher. Hand cream is a care product that is applied to the palms and backs of the hands in the form of a cream that can help restore hydration and skin function due to dry and rough skin. Pineapple peel contains flavonoids, vitamin C, and bromelain enzymes that can ward off free radicals caused by sun exposure so that it has the potential to be formulated into anti-aging preparations. Objective: To formulate ethanol extract of pineapple peel (Ananas comosus (L.) Merr.) into hand cream and to test the effectiveness as anti-aging agent. Methods: This research included the stages of processing pineapple peel, making extracts by percolation method using 70% ethanol solvent, testing the antioxidant activity of pineapple peel extract using DPPH (2,2-diphenyl-1-picryhydrazyl) method, and hand cream formulations with the addition of pineapple peel extract with respective concentration of 5% (F1), 7.5% (F2), 10% (F3) and without pineapple peel extract (F0). Evaluation of hand cream preparations included organoleptic test, homogeneity, emulsion type, pH, viscosity, and physical stability at room temperature storage for 12 weeks and cycling test for 4 weeks. Anti-aging effectiveness testing was carried out during the 4 weeks treatment period, by measuring parameters such as moisture, pores, blemishes and wrinkles on the skin of the backs of volunteer hands which were measured once a week using a skin analyzer. Results: The results of the antioxidant activity test of the ethanol extract of pineapple peel were included in the strong category with an IC50 value of 88.21 μg/mL. The hand cream preparation produced was homogeneous, O/W emulsion type, pH value 5.09-6.56, viscosity value 4086.76-6104.96 cPs, stable during 12 weeks of storage at room temperature and stable in the cycling test for 4 weeks. Hand cream preparations with a concentration of 10% have better effectiveness than 0%, 5% and 7.5% which results in an average percent moisture recovery of 77.60%, pores 62.92%, blemishes 55.65%, and wrinkles 45.92%. Conclusion: Ethanol extract of pineapple peel can be formulated into hand cream preparations and meets the requirements of preparation evaluation and has the best anti-aging effectiveness at a concentration of 10%.en_US
dc.language.isoiden_US
dc.publisherUniversitas Sumatera Utaraen_US
dc.subjecthand creamen_US
dc.subjectpineapple peel (Ananas comosus (L.) Merr.)en_US
dc.subjectanti-agingen_US
dc.subjectformulationen_US
dc.subjectSDGsen_US
dc.titleFormulasi dan Uji Aktivitas Anti-Aging Sediaan Hand Cream yang Mengandung Ekstrak Etanol Kulit Buah Nanas (Ananas comosus (L.) Merr.)en_US
dc.title.alternativeFormulation and Anti-Aging Activity Testing of Hand Cream Containing Ethanol Extract of Pineapple Peel (Ananas comosus (L.) Merr.)en_US
dc.typeThesisen_US
dc.identifier.nimNIM201501078
dc.identifier.nidnNIDN0026127706
dc.identifier.kodeprodiKODEPRODI48201#Farmasi
dc.description.pages137 Pagesen_US
dc.description.typeSkripsi Sarjanaen_US


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