Identifikasi Drug Related Problems pada Pasien Penyakit Ginjal Kronis di Rumah Sakit Prof. Dr. Chairuddin Panusunan Lubis Tahun 2023

Abstract

Background: Chronic kidney disease (CKD) is an abnormality of kidney structure or function, present for ≥ 3 months, with implications for health. The high number of medications used by CKD patients can increase the potential for Drug-Related Problems (DRPs) which can interfere with desired health outcomes. Objective: This study aimed to determine the occurrence of DRPs in chronic kidney disease patients admitted to Prof. Dr. Chairuddin Panusunan Lubis Hospital in 2023. Methods: This study was a descriptive retrospective cross-sectional study conducted at Prof. dr. Chairuddin Panusunan Lubis Hospital. Data were obtained from the medical records of CKD inpatients in 2023 (n=51). The sampling technique used was total sampling. The occurrence of DRPs was identified based on the Pharmaceutical Care Network Europe (PCNE) V9.1 classification, which includes problems categories (P1-P3) and causes (C1-C6). Results: There were 28 females (54.90%) and 23 males (45.10%), with an average age of 46.8±11.5 years. The highest stage of CKD was stage 5 (78.43%). The most common comorbid condition was anemia (84.31%), with the most frequently used medication being antihypertensives in the Calcium Channel Blocker class (88.24%). Among the 51 medical records, 21 (41,17%) showed the occurrence of DRPs, consisting of 26 Problems (P) categorized under P1. Treatment effectiveness (46,15%) and P2. Treatment safety (53,85%), and 26 Causes (C) categorized under C1. Drug selection (57,69%) and C3. Dose selection (42,31%). Conclusion: Drug-Related Problems (DRPs) occurred in chronic kidney disease patients admitted to Prof. dr. Chairuddin Panusunan Lubis Hospital in 2023.