| dc.description.abstract | Background : Infectious diseases are one of the serious health issues that require
attention. Infectious diseases can easily spread to others, thus requiring
immediate attention. One of the bacteria that causes infections is Staphylococcus
aureus. Communities in various countries have utilized coffee plants to address
various health issues. One method is by using coffee fruit skin waste as an
antibacterial agent.
Objective : The aim of this research is to determine the minimum inhibitory
concentration of silver nanoparticles coffee fruit skin waste extract (Coffea
canephora) against Staphylococcus aureus.
Method : Antibacterial activity test of silver nanoparticles coffee fruit skin waste
extract (Coffea canephora) against Staphylococcus aureus using agar diffution
using the clindamycin as positive control, and DMSO as the negative control
Results : The test results showed that the antibacterial of of silver nanoparticles
coffee fruit skin waste extract (Coffea canephora) against Staphylococcus aureus
had activity which was indicated by the presence of a clear zone when
determining the diameter of the inhibition zone. The test concentrations used were
75 ppm, 50 ppm, 25 ppm, 12,5 ppm, and 6,25 ppm, with the average diameter of
the inhibition zone respectively being 10,33 mm, 10,03 mm, 9,6 mm, 8,53 mm, and
6,6 mm.
Conclusion : The minimum inhibitory concentration of silver nanoparticles coffee
fruit skin waste extract (Coffea canephora) against Staphylococcus aureus is 6,25
ppm. | en_US |
